There may be many situations when IVF is the only option of realising your baby dream. It can be both a physically challenging and emotionally draining process, not to mention the monetary expense. Therefore, it is important to support the health and integrity of both egg and sperm to ensure optimal outcomes.
Recently, studies on inositol supplementation during in vitro fertilization program (IVF) have gained particular importance due to the effect of this molecule on reducing insulin resistance improving ovarian function, oocyte quality, and embryo and pregnancy rates and reducing gonadotropin amount during stimulation. Inositol and its isoforms, especially myoinositol (MYO), are often used as prestimulation therapy in infertile patients undergoing IVF cycle. Inositol supplementation started three months before ovarian stimulation, resulting in significant improvements in hormonal responses, reducing the amount of FSH necessary for optimal follicle development and serum levels of 17beta-estradiol measured the day of hCG injection.
As shown by growing number of trials, MYO supplementation improves oocyte quality by reducing the number of degenerated and immature oocytes, in this way increasing the quality of embryos produced. Inositol can also improve the quality of sperm parameters in those patients affected by oligoasthenoteratozoospermia. (Simi et al., 2017)
Preparation is the key
In my book I spend many pages explaining why preconception care is so important. One could even argue that it becomes more so if contemplating IVF as this process places additional strain on both the egg and sperm, so quality is key. After all, it’s not only about getting pregnant, it is about giving birth to a baby that will grow into a healthy adult and benefit from good health throughout its life.
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